Event information

iCAN science seminar with Dr. Ruben van Boxtel on Jun 4

You are warmly welcome to iCAN science seminar on Tue 4.6.2024 at 13:30-14:30, Biomedicum 1, Lecture Hall 1 and Zoom. (Meeting ID: 648 0498 6682 Passcode: 366409)

Speaker: Dr. Ruben van Boxtel, Princes Máxima Center of Pediatric Oncology and Oncode Institute

Title: Tracing the origin of pediatric leukemia using single-cell genome sequencing



Short bio:
Ruben van Boxtel has pioneered the development of experimental and computational approaches to study the genomes of human stem cells. Using these methods, his group showed that mutation accumulation varies across different tissues throughout human life. In 2017, Ruben was appointed as a group leader at the Princess Máxima Center for Pediatric Oncology, where he focusses on studying why children get leukemia and lymphoma, and what the genotoxic effects of treatment are in the hematopoietic system. Using in-depth mutational analyses, the group of Ruben has discovered mutational cancer signatures caused by a genotoxic gut bacterium and antiviral drugs. 

Ruben received an NWO Vidi award in 2017 by the Netherlands Organization for Scientific Research for his research on studying genomic integrity of human stem cells throughout life. In addition, Ruben received an ERC Consolidator award by the European Research Council in 2019 to study the causes of therapy-related myeloid neoplasms in childhood cancer survivors. In the same year, he was selected as an Oncode Investigator, which a collective institute bringing together the best fundamental cancer researchers in the Netherlands. In 2022, Ruben received the NYSCF Robertson Stem Cell Investigator Award for his work on studying long-term toxicity in the hematopoietic system of childhood cancer survivors. In 2024, he received an NWO Vici award for studying the etiology of late adverse effects in childhood cancer survivors.


Link for those joining on Zoom

https://helsinki.zoom.us/j/64804986682?pwd=ME8rOVhucnQ5YXE1VVdpck5BN25BZz09

Meeting ID: 648 0498 6682 Passcode: 366409


Coffee will be served before the seminar.

For more information, please contact ican@helsinki.fi